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美国明尼苏达学招聘生物信息学博后


招聘生物信息学博后

We are looking for a highly motivated candidate specializing in Bioinformatics to join the Computational Cancer Genomics lab of Dr. Rendong Yang at the Hormel Institute, University of Minnesota. The goal of this position will develop novel computational algorithm(s), perform data analysis, collaborate with biologists and physicians, and present/publish the results in scientific conferences/journals. 

The main focus is to explore the functional consequences of somatic alterations in cancer patients, to identify driver alterations, and to understand the genetic mechanisms of cancer progression and drug resistance by integrating multi-dimensional data from large-scale cancer studies such as The Cancer Genome Atlas (TCGA).QualificationsA Ph.D in Bioinformatics/Computational Biology/Computer Science/Statistics/Physics/Biology or a related field is required along with experience in Linux, proficiency in at least one programming languages (e.g. Python, R, Perl, Java, C/C++, Matlab) and experiences with high- throughput sequencing data (WGS, WES, RNA-Seq, ChIP-Seq) analysis. 

The candidate must demonstrate effective verbal and written communication skills.About the LabOur laboratory is interested in the integrative analysis of large-scale, multi-dimensional genomic data to understand the initiation and progression of diseases. The research projects involve in the development of highly accurate and sensitive computational methods for analyzing large-scale genomic data, especially in the area of detecting and analyzing genetic variations and somatic mutations. 

Example projects span from technique-driven research that aims developing algorithms for a wide range of applications (e.g. Yang et al., Bioinformatics 2010; Yang et al., BMC Genomics 2014; Yang et al., Genome Medicine 2015), to hypothesis-driven investigation of specific biological problems where the main goal is the discovery and advancement of biological knowledge (e.g. Asangani et al., Nature 2014; Henzler et al., Nature Communications 2016; Katerndahl et al., Nature Immunology 2017).About the Hormel InstituteThe Hormel Institute, a biomedical research center of the University of Minnesota, was established in 1942 and has an excellent reputation and long history for producing world-class medical research. 

The Institute’s research success has resulted in a second major expansion of its research facilities and includes an additional new state-of-the-art laboratory building that opened in January 2016. The Hormel Institute offers its research scientists complete access to state-of-the- art cutting edge equipment that includes a cryo-electron microscope (Titan Krios and Tecnai G2 Spirit Biotwin); 

FACS cell sorter; confocal microscopy; flow cytometry; protein crystallography robotics and defraction system; nano-HPLC-AB SCIEX triple TOF 5600 mass spectrometry; a Blue Gene/L and 3 racks of Linux GPU supercomputers for computational biology and bioinformatics; and spectrophotometers.How To ApplySend a cover letter, CV to Dr. Rendong Yang (yang4414@umn.edu)

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明尼苏达大学

明尼苏达大学(University of Minnesota, Twin Cities),简称U of M或UMN,通常指明尼苏达大学双城校区,是一所位于美国明尼苏达州双子城(即明尼阿波利斯与圣保罗)的世界著名公立研究型大学,为明尼苏达大学系统历史最悠久,规模最大的分校,亦常被直接称为明尼苏达大学。自1851年建校至今,学校已拥有众多声名显赫的校友,目前已有29位诺贝尔奖得主,1位前美国首席大法官,2位前美国副总统,以及多位名列美国财富500强的企业巨子,具有优秀的教育和服务社会的传统。许多世界顶尖的技术和发明在明大诞生:飞行记录器(黑匣子)、可收取式汽车安全带、心脏起搏器、心肺呼吸器等。明大拥有肾脏移植机构。

明尼苏达大学是美国十大联盟(Big Ten Conference)、美国大学协会(AAU)的成员校之一,也是国际21世纪学术联盟的成员之一,为世界著名的本科、研究生教育学府和研究机构,被誉为“公立常春藤”。

明尼苏达大学也是美国最具综合性的高等学府之一,常年位居世界大学排行榜前列。明尼苏达大学在2017年USNews世界大学排名中位列全球第38位,2016-2017年泰晤士高等教育世界大学排名第53位,而2016上海交大ARWU世界大学学术排名则将明大评为全球第33位。


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